[H] Dual Monitor Scroll / Mouse Trapping Issues

This happens on both windowed and full-screen mode.

Changing the Confine Mouse Cursor settings from Automatic to On has no effect. The mouse still escapes the screen.

Having Windows Key or Alt-tab disabled makes no difference. I usually leave alt-tab enabled, though, to be able to fix the issue when it occurs. The problem isn't with the app losing focus to key presses.

I've also excluded the possibility of this being caused by another application stealing focus. I've reinstalling the OS (Win 7 Ultimate) and run with no active applications, including no A/V and minimal enabled services. The issue occurs at random, reliable intervals and only when using two monitors.

Things work normally in most games for a few minutes, then the mouse escapes one time and I'm stuck without mouse-scroll in that direction until I use the alt-tab trick.

It's very repeatable and occurs every game within the first few minutes.

I can still scroll with the keyboard arrows or by clicking around the mini-map. It's just mouse-scrolling by moving the mouse to the edge in the righthand-direction that's broken.

The problem isn't just because my mouse leaves the screen. I can forcibly trap the mouse within the monitor or an area of the game using a variety of programs like MultiMon. But the issue where I'm stuck without mouse-scrolling still occurs, even though the cursor remains in the screen the whole time.

This is a graphics card or driver related issue. Dual monitor worked just fine with my old, stuttery graphics card. I'm on a Radeon 6850 now, and have tried a few (at least 3) sets of different drivers to no avail.

My workaround right now is to disable the second monitor screen before I play, then reenable it afterwards. This is a pain because I always forget to disable it until I'm in the middle of a game. Or I just leave it off for weeks at a time, defeating the point of a having second monitor.

Random details: Monitor sizes are 1920 x 1080 and 1280 x 1024. One over HDMI the other DVI. Same as I used before this graphics card. I usually play on Ultra 1920 x 1080, but I've tried High and Medium without it helping the issue.

My most preferable solution would be pointing to a graphics driver that works (I'm on the latest now). Second to that would be patching SC2 in some way. I wouldn't mind getting a third-party program to fix this, but just mouse-trapping on one monitor doesn't help. Lastly, as a work-around, I wouldn't mind if SC2 or a batch file that kicks off SC2 just disables my second monitor while I have the game open. Anything, really, to fix the issue and allow me to preserve my current set up while not playing SC2.