I know that the game no longer opens the help menu with F1, but removing it also helps to guide your fingers so that you can find F2 as the "first" key, instead of F1 which doesn't do anything. Plus those players have been used to that for years, right?
I find it strange especially considering that some SC2 pros like Innovation still remove it (at least until a couple of years ago when I saw his keyboard).
What are all these F1 keys doing here?!!